Asymmetric Michael reaction of aldehydes and nitroalkenes

Yujiro Hayashi, Shin Ogasawara, Yasuyuki Ueda, Keisuke Suzuki

Research output: Contribution to journalArticlepeer-review

Abstract

A procedure yielding alcohol 2 as a yellow oil is presented. The main paraphernalia used is a three‐necked round‐bottomed flask equipped with an egg‐shaped, Teflon‐coated, magnetic stir bar, an internal thermometer, a two‐way stopcock with a hose, and a three‐way stopcock connected to a nitrogen inlet hose. A brief summary of asymmetric Michael reaction of aldehydes and nitroalkenes concludes the chapter.

Original languageEnglish
JournalOrganic Syntheses
Volume94
DOIs
Publication statusPublished - 2018 Jun 20

Keywords

  • Aldehydes
  • Diastereoselectivity
  • Diphenylprolinol trimethylsilyl ether
  • Michael reaction
  • Nitroalkenes
  • Sodium borohydride

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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