Asymmetric michael reaction of aldehyde and β-substituted α-nitroacrylate catalyzed by diphenylprolinol silyl ether

Daisuke Sakamoto, Yujiro Hayashi

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The asymmetric Michael reaction of an aldehyde and β-substituted α-nitroacrylate, catalyzed by diphenylprolinol silyl ether, was successfully carried out and good yield was achieved. This reaction has broad substrate generality. Moreover, the product can be easily converted to pyrrolidine or lactone.

Original languageEnglish
Pages (from-to)833-835
Number of pages3
JournalChemistry Letters
Volume47
Issue number7
DOIs
Publication statusPublished - 2018 Jan 1

Keywords

  • Asymmetric reaction
  • Michael reaction
  • Organocatalyst

ASJC Scopus subject areas

  • Chemistry(all)

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