Abstract
A highly diastereo‐ and enantio‐selective intramolecular ene reaction was developed by employing a chiral titanium reagent generated in situ from TiCl2(OPri)2 and a tartrate‐derived chiral 1,4‐diol. This reaction afforded masked cyclohexanone and cyclopentanone derivatives with high optical purities which were synthetically useful chiral building blocks. From the intramolecular ene product (—)‐ε‐cadinene was synthesized by the use of the newly developed intramolecular Michael reaction.
Original language | English |
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Pages (from-to) | 261-271 |
Number of pages | 11 |
Journal | Israel Journal of Chemistry |
Volume | 31 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1991 |
Externally published | Yes |
ASJC Scopus subject areas
- Chemistry(all)