Asymmetric Diels-Aider reactions of TMHD-acrylate using TiCl 4·(ArnHg)m complexed Lewis acids

Isao Kadota, Katsumi Kobayashi, Naoki Asao, Yoshinori Yamamoto

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    Diels-Alder reaction of (3R,5S)-5-benzoyloxy-2,2,6,6-tetramethyl-3-heptyl acrylate (TMHD-acrylate) 1 with cyclopentadiene in the presence of TiCl 4·(ArnHg)m complexed Lewis acids gives (1R,4R,6R)-2-norbornene-6-carboxylate derivative 4 predominantly, whereas the reaction in the presence of TiCl4 alone affords its enantiomer 2 preferentially.

    Original languageEnglish
    Pages (from-to)1271-1272
    Number of pages2
    JournalJournal of the Chemical Society, Chemical Communications
    Issue number12
    DOIs
    Publication statusPublished - 1995 Dec 1

    ASJC Scopus subject areas

    • Molecular Medicine

    Fingerprint Dive into the research topics of 'Asymmetric Diels-Aider reactions of TMHD-acrylate using TiCl <sub>4</sub>·(Ar<sub>n</sub>Hg)<sub>m</sub> complexed Lewis acids'. Together they form a unique fingerprint.

  • Cite this