Asymmetric autocatalysis induced by chiral hydrocarbon [2.2]paracyclophanes

Itaru Sato, Atsushi Ohno, Yohei Aoyama, Toshinari Kasahara, Kenso Soai

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Chiral hydrocarbon [2.2]paracyclophanes act as chiral initiators in asymmetric autocatalysis in the addition of diisopropylzinc to pyrimidine-5-carbaldehyde and give highly enantiomerically enriched 5-pyrimidyl alkanol with a reversed sense of the enantioselectivity to that of other [2.2]paracyclophanes with heteroatoms.

Original languageEnglish
Pages (from-to)244-246
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume1
Issue number2
DOIs
Publication statusPublished - 2003 Jan 21

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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