Abstract
The asymmetric activation of binaphthol (BINOL)-zirconium catalysts is described on the enantioselective allylation of benzaldehyde with allyltin reagents. This model reaction has been used with the intention of establishing a protocol for a zirconium-based catalyst system, to be followed by structural studies. Initial results are reported that characterise a number of interesting features, namely the influence of an induction period and a high level of asymmetric activation obtained after addition of a product-like activator.
| Original language | English |
|---|---|
| Pages (from-to) | 717-721 |
| Number of pages | 5 |
| Journal | Chirality |
| Volume | 10 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1998 Jan 1 |
| Externally published | Yes |
Keywords
- Allylation
- Asymmetric activation
- Binaphthol (BINOL)
- Chiral high- performance liquid chromatography
- Enantioselective carbon-carbon bond formation
- Induction period
- Product-like activator
- Zirconium
ASJC Scopus subject areas
- Analytical Chemistry
- Catalysis
- Pharmacology
- Drug Discovery
- Spectroscopy
- Organic Chemistry