Asymmetric activation of chiral BINOL-zirconium catalysts: Effect of a product-like activator

Thorsten Volk, Toshinobu Korenaga, Satoru Matsukawa, Masahiro Terada, Koichi Mikami

Research output: Contribution to journalArticlepeer-review

15 Citations (Scopus)

Abstract

The asymmetric activation of binaphthol (BINOL)-zirconium catalysts is described on the enantioselective allylation of benzaldehyde with allyltin reagents. This model reaction has been used with the intention of establishing a protocol for a zirconium-based catalyst system, to be followed by structural studies. Initial results are reported that characterise a number of interesting features, namely the influence of an induction period and a high level of asymmetric activation obtained after addition of a product-like activator.

Original languageEnglish
Pages (from-to)717-721
Number of pages5
JournalChirality
Volume10
Issue number7
DOIs
Publication statusPublished - 1998 Jan 1
Externally publishedYes

Keywords

  • Allylation
  • Asymmetric activation
  • Binaphthol (BINOL)
  • Chiral high- performance liquid chromatography
  • Enantioselective carbon-carbon bond formation
  • Induction period
  • Product-like activator
  • Zirconium

ASJC Scopus subject areas

  • Analytical Chemistry
  • Catalysis
  • Pharmacology
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

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