Astatine-211 imaging by a Compton camera for targeted radiotherapy

Yuto Nagao, Mitsutaka Yamaguchi, Shigeki Watanabe, Noriko S. Ishioka, Naoki Kawachi, Hiroshi Watabe

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Astatine-211 is a promising radionuclide for targeted radiotherapy. It is required to image the distribution of targeted radiotherapeutic agents in a patient's body for optimization of treatment strategies. We proposed to image 211At with high-energy photons to overcome some problems in conventional planar or single-photon emission computed tomography imaging. We performed an imaging experiment of a point-like 211At source using a Compton camera, and demonstrated the capability of imaging 211At with the high-energy photons for the first time.

Original languageEnglish
Pages (from-to)238-243
Number of pages6
JournalApplied Radiation and Isotopes
Volume139
DOIs
Publication statusPublished - 2018 Sep

Keywords

  • Astatine-211
  • Compton camera
  • Monte Carlo simulation
  • Targeted radiotherapy

ASJC Scopus subject areas

  • Radiation

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