Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds

Yoshiyuki Takeda; Jinglu Shi; Masato Oikawa; Makoto Sasaki

doi:10.1021/ol8000377

Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds

Yoshiyuki Takeda, Jinglu Shi, Masato Oikawa, Makoto Sasaki

LIF - Molecular and Chemical Life Science

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

The complete absolute configuration of goniodomin A, an actin-targeting polyether macrolide isolated from the marine dinoflagellate Alexandrium hiranoi, was established from analysis of ROESY experiments and coupling constants, synthesis of suitable model compounds for NMR spectroscopic comparisons, degradation experiments, and correlation with synthetic reference compounds.

Original language	English
Pages (from-to)	1013-1016
Number of pages	4
Journal	Organic letters
Volume	10
Issue number	5
DOIs	https://doi.org/10.1021/ol8000377
Publication status	Published - 2008 Mar 6

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/ol8000377

Cite this

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abstract = "The complete absolute configuration of goniodomin A, an actin-targeting polyether macrolide isolated from the marine dinoflagellate Alexandrium hiranoi, was established from analysis of ROESY experiments and coupling constants, synthesis of suitable model compounds for NMR spectroscopic comparisons, degradation experiments, and correlation with synthetic reference compounds.",

author = "Yoshiyuki Takeda and Jinglu Shi and Masato Oikawa and Makoto Sasaki",

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AU - Takeda, Yoshiyuki

AU - Shi, Jinglu

AU - Oikawa, Masato

AU - Sasaki, Makoto

PY - 2008/3/6

Y1 - 2008/3/6

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AB - The complete absolute configuration of goniodomin A, an actin-targeting polyether macrolide isolated from the marine dinoflagellate Alexandrium hiranoi, was established from analysis of ROESY experiments and coupling constants, synthesis of suitable model compounds for NMR spectroscopic comparisons, degradation experiments, and correlation with synthetic reference compounds.

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Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds

Abstract

ASJC Scopus subject areas

UN SDGs

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