Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds

Yoshiyuki Takeda; Jinglu Shi; Masato Oikawa; Makoto Sasaki

doi:10.1021/ol8000377

Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds

Yoshiyuki Takeda, Jinglu Shi, Masato Oikawa, Makoto Sasaki

LIF - Molecular and Chemical Life Science

Research output: Contribution to journal › Article › peer-review

31 Citations (Scopus)

Abstract

The complete absolute configuration of goniodomin A, an actin-targeting polyether macrolide isolated from the marine dinoflagellate Alexandrium hiranoi, was established from analysis of ROESY experiments and coupling constants, synthesis of suitable model compounds for NMR spectroscopic comparisons, degradation experiments, and correlation with synthetic reference compounds.

Original language	English
Pages (from-to)	1013-1016
Number of pages	4
Journal	Organic letters
Volume	10
Issue number	5
DOIs	https://doi.org/10.1021/ol8000377
Publication status	Published - 2008 Mar 6

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1021/ol8000377

Cite this

@article{a79c9f1a93c146a3a8a44ebd393335dd,

title = "Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds",

abstract = "The complete absolute configuration of goniodomin A, an actin-targeting polyether macrolide isolated from the marine dinoflagellate Alexandrium hiranoi, was established from analysis of ROESY experiments and coupling constants, synthesis of suitable model compounds for NMR spectroscopic comparisons, degradation experiments, and correlation with synthetic reference compounds.",

author = "Yoshiyuki Takeda and Jinglu Shi and Masato Oikawa and Makoto Sasaki",

year = "2008",

month = mar,

day = "6",

doi = "10.1021/ol8000377",

language = "English",

volume = "10",

pages = "1013--1016",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "5",

}

TY - JOUR

T1 - Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds

AU - Takeda, Yoshiyuki

AU - Shi, Jinglu

AU - Oikawa, Masato

AU - Sasaki, Makoto

PY - 2008/3/6

Y1 - 2008/3/6

N2 - The complete absolute configuration of goniodomin A, an actin-targeting polyether macrolide isolated from the marine dinoflagellate Alexandrium hiranoi, was established from analysis of ROESY experiments and coupling constants, synthesis of suitable model compounds for NMR spectroscopic comparisons, degradation experiments, and correlation with synthetic reference compounds.

AB - The complete absolute configuration of goniodomin A, an actin-targeting polyether macrolide isolated from the marine dinoflagellate Alexandrium hiranoi, was established from analysis of ROESY experiments and coupling constants, synthesis of suitable model compounds for NMR spectroscopic comparisons, degradation experiments, and correlation with synthetic reference compounds.

UR - http://www.scopus.com/inward/record.url?scp=41949102664&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=41949102664&partnerID=8YFLogxK

U2 - 10.1021/ol8000377

DO - 10.1021/ol8000377

M3 - Article

C2 - 18266381

AN - SCOPUS:41949102664

VL - 10

SP - 1013

EP - 1016

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 5

ER -

Assignment of the absolute configuration of goniodomin a by NMR spectroscopy and synthesis of model compounds

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this