Assembly system of direct modified superparamagnetic iron oxide nanoparticles for target-specific MRI contrast agents

Kazuo Tanaka, Narufumi Kitamura, Masahito Morita, Toshiro Inubushi, Yoshiki Chujo

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

We report the direct modification of SPIOs with a biomolecule and the target-specific assembly system of these modified SPIOs for using MRI contrast agents. The transverse relaxation rate of the aqueous solutions containing the modified SPIOs was altered by the dispersion state.

Original languageEnglish
Pages (from-to)5463-5465
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume18
Issue number20
DOIs
Publication statusPublished - 2008 Oct 15
Externally publishedYes

Keywords

  • Aptamer
  • Assembly
  • Contrast agent
  • MRI
  • Nanoparticle
  • SPIO

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Assembly system of direct modified superparamagnetic iron oxide nanoparticles for target-specific MRI contrast agents'. Together they form a unique fingerprint.

Cite this