Ascidian embryonic development: An emerging model system for the study of cell fate specification in chordates

Gaku Kumano, Hiroki Nishida

Research output: Contribution to journalReview article

68 Citations (Scopus)

Abstract

The ascidian tadpole larva represents the basic body plan of all chordates in a relatively small number of cells and tissue types. Although it had been considered that ascidians develop largely in a determinative way, whereas vertebrates develop in an inductive way, recent studies at the molecular and cellular levels have uncovered several similarities in the way developmental fates are specified. In this review, we describe ascidian embryogenesis and its cell lineages, introduce several characteristics of ascidian embryos, describe recent advances in understanding of the mechanisms of cell fate specification, and discuss them in the context of what is known in vertebrates and other organisms.

Original languageEnglish
Pages (from-to)1732-1747
Number of pages16
JournalDevelopmental Dynamics
Volume236
Issue number7
DOIs
Publication statusPublished - 2007 Jul 1
Externally publishedYes

Keywords

  • Ascidian
  • Cell fate specification
  • Embryogenesis
  • Embryonic axis
  • Embryonic induction
  • Maternal determinants

ASJC Scopus subject areas

  • Developmental Biology

Fingerprint Dive into the research topics of 'Ascidian embryonic development: An emerging model system for the study of cell fate specification in chordates'. Together they form a unique fingerprint.

  • Cite this