Arterial and biliary complications after living donor liver transplantation: a single-center retrospective study and literature review

Shigehito Miyagi, Yuta Kakizaki, Kenji Shimizu, Koji Miyazawa, Wataru Nakanishi, Yasuyuki Hara, Kazuaki Tokodai, Chikashi Nakanishi, Takashi Kamei, Noriaki Ohuchi, Susumu Satomi

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Aim: The mortality of patients on the waiting list for deceased donor liver transplantation (DDLT) is high, especially in countries where donation rates are low. Thus, living donor liver transplantation (LDLT) is an attractive option. However, compared with DDLT, LDLT is associated with increased rates of arterial and biliary complications. We examined the rates of complications and risk factors following LDLT. Methods: We retrospectively investigated and compared the rates of complications of DDLT and LDLT in our institute. We also performed univariate and multivariate analyses to identify the independent risk factors for these complications. The complications and specific disadvantages of LDLT were reviewed and discussed. Results: The incidence rate of arterial complications in LDLT was 6.0%, compared with 3.2% (13/441) in DDLT. A multivariate analysis identified low body weight (P = 0.032) as the only independent risk factor for hepatic artery thrombosis. The rate of all biliary complications in LDLT was 17.3%, compared with 18.7% in DDLT. The risk factors for biliary stricture identified by the multivariate analysis were recurrent cholangitis and the number of bile ducts. The durations of hospital stay and overall survival rates were similar between the two groups. Conclusion: Given the shortage of deceased donor organs, we believe that LDLT is acceptable in an attempt to meet demand.

Original languageEnglish
Pages (from-to)131-139
Number of pages9
JournalSurgery today
Volume48
Issue number2
DOIs
Publication statusPublished - 2018 Feb 1

Keywords

  • Complications
  • Deceased donor
  • Liver transplantation
  • Living donor

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Arterial and biliary complications after living donor liver transplantation: a single-center retrospective study and literature review'. Together they form a unique fingerprint.

Cite this