Application of tyramide signal amplification system to immunohistochemistry: A potent method to localize antigens that are not detectable by ordinary method

Yoshinobu Toda; Katsuhiko Kono; Hitoshi Abiru; Kumiko Kokuryo; Mareyuki Endo; Hiroshi Yaegashi; Manabu Fukumoto

doi:10.1046/j.1440-1827.1999.00875.x

Application of tyramide signal amplification system to immunohistochemistry: A potent method to localize antigens that are not detectable by ordinary method

Yoshinobu Toda, Katsuhiko Kono, Hitoshi Abiru, Kumiko Kokuryo, Mareyuki Endo, Hiroshi Yaegashi, Manabu Fukumoto

Division of Cancer Science

Research output: Contribution to journal › Article › peer-review

96 Citations (Scopus)

Abstract

Tyramide signal amplification-avidin-biotin complex (TSA-ABC) method is a powerful technique used to detect antigens that are not detectable by ordinary immunohistochemistry. It is worth trying in cases where localization of antigens by the conventional method has failed and antibodies are precious.

Original language	English
Pages (from-to)	479-483
Number of pages	5
Journal	Pathology international
Volume	49
Issue number	5
DOIs	https://doi.org/10.1046/j.1440-1827.1999.00875.x
Publication status	Published - 1999 Jul 14

Keywords

Antigen retrieval
Archival sections
Immunohistochemistry
Tyramid signal amplification

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1046/j.1440-1827.1999.00875.x

Cite this

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abstract = "Tyramide signal amplification-avidin-biotin complex (TSA-ABC) method is a powerful technique used to detect antigens that are not detectable by ordinary immunohistochemistry. It is worth trying in cases where localization of antigens by the conventional method has failed and antibodies are precious.",

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author = "Yoshinobu Toda and Katsuhiko Kono and Hitoshi Abiru and Kumiko Kokuryo and Mareyuki Endo and Hiroshi Yaegashi and Manabu Fukumoto",

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AU - Kono, Katsuhiko

AU - Abiru, Hitoshi

AU - Kokuryo, Kumiko

AU - Endo, Mareyuki

AU - Yaegashi, Hiroshi

AU - Fukumoto, Manabu

PY - 1999/7/14

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KW - Antigen retrieval

KW - Archival sections

KW - Immunohistochemistry

KW - Tyramid signal amplification

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Application of tyramide signal amplification system to immunohistochemistry: A potent method to localize antigens that are not detectable by ordinary method

Abstract

Keywords

ASJC Scopus subject areas

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