Apatite-forming ability of glass-ceramic apatite-wollastonite - Polyethylene composites: Effect of filler content

J. A. Juhasz, S. M. Best, W. Bonfield, M. Kawashita, N. Miyata, T. Kokubo, T. Nakamura

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

The bioactivity of a range of glass-ceramic apatite-wollastonite (A-W) - polyethylene composites (AWPEXs) with glass-ceramic A-W volume percentages ranging from 10 to 50, has been investigated in an acellular simulated body fluid (SBF) with ion concentrations similar to those of human blood plasma. The formation of a biologicallyactive apatite layer on the composite surface after immersion in SBF was demonstrated by thin-film X-ray diffraction (TF-XRD) and field-emission scanning electron microscopy (FE-SEM). An apatite layer was formed on all the composites, with the rate of formation increasing with an increase in glass-ceramic A-W percentage. For composites with glass-ceramic A-W filler contents ≥30 vol%, the apatite layer was formed within 12h of immersion, which is a comparable time for apatite formation on monolithic glass-ceramic A-W. Inductively coupled plasma atomic emission spectroscopy (ICP-AES) demonstrated that the apatite formation on AWPEX samples with 50vol% filler content occurred in a manner similartothatseen on pure glass-ceramic A-W, in that the calcium, silicon, and magnesium ion concentrations increased and, conversely, a decrease was observed in the phosphate ion concentration. These results indicate that a suitable in vitro response was achieved on a composite incorporating particulate glass-ceramic A-W with a particularly favorable response being observed on the AWPEX sample with 50vol% filler content.

Original languageEnglish
Pages (from-to)489-495
Number of pages7
JournalJournal of Materials Science: Materials in Medicine
Volume14
Issue number6
DOIs
Publication statusPublished - 2003 Jun 1

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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