Apatite-forming ability of ethylene-vinyl alcohol copolymer modified with Ti-OH groups

Tadashi Kokubo, Ayako Oyane, Masakazu Kawashita, Masahiko Minoda, Takeaki Miyamoto, Takashi Nakamura

Research output: Contribution to journalConference articlepeer-review


The surface of ethylene-vinyl alcohol copolymer (EVOH) was modified with Ti-OH groups by treatments with a silane coupling agent and a titania solution. Arrangement of the Ti-OH groups on the specimen was changed into anatase by a treatment with ultra-pure water or a HCl aqueous solution. Thus surface-modified specimen formed apatite on its surface in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma within 2 d. The present surface-modification of EVOH would be useful for producing a bone substitute with bone-bonding ability as well as analogous mechanical properties to those of natural bone.

Original languageEnglish
Pages (from-to)617-620
Number of pages4
JournalKey Engineering Materials
Publication statusPublished - 2002 Jan 1
Event14th International Symposium on Ceramics in Medicine-Annual Meeting of the International Society for Ceramics in Medicine BIOCERAMICS'01 (ISCM) - Palm Springs, CA, United States
Duration: 2001 Nov 142001 Nov 17


  • Anatase
  • Apatite
  • Ethylene-vinyl alcohol copolymer
  • Simulated body fluid
  • Ti-OH group

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering


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