Apatite-forming ability of ethylene-vinyl alcohol copolymer modified with Ti-OH groups

Tadashi Kokubo; Ayako Oyane; Masakazu Kawashita; Masahiko Minoda; Takeaki Miyamoto; Takashi Nakamura

Apatite-forming ability of ethylene-vinyl alcohol copolymer modified with Ti-OH groups

Tadashi Kokubo, Ayako Oyane, Masakazu Kawashita, Masahiko Minoda, Takeaki Miyamoto, Takashi Nakamura

MEN - Biomedical Engineering

Research output: Contribution to journal › Conference article › peer-review

Abstract

The surface of ethylene-vinyl alcohol copolymer (EVOH) was modified with Ti-OH groups by treatments with a silane coupling agent and a titania solution. Arrangement of the Ti-OH groups on the specimen was changed into anatase by a treatment with ultra-pure water or a HCl aqueous solution. Thus surface-modified specimen formed apatite on its surface in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma within 2 d. The present surface-modification of EVOH would be useful for producing a bone substitute with bone-bonding ability as well as analogous mechanical properties to those of natural bone.

Original language	English
Pages (from-to)	617-620
Number of pages	4
Journal	Key Engineering Materials
Volume	218-220
Publication status	Published - 2002 Jan 1
Event	14th International Symposium on Ceramics in Medicine-Annual Meeting of the International Society for Ceramics in Medicine BIOCERAMICS'01 (ISCM) - Palm Springs, CA, United States Duration: 2001 Nov 14 → 2001 Nov 17

Keywords

Anatase
Apatite
Ethylene-vinyl alcohol copolymer
Simulated body fluid
Ti-OH group

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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title = "Apatite-forming ability of ethylene-vinyl alcohol copolymer modified with Ti-OH groups",

abstract = "The surface of ethylene-vinyl alcohol copolymer (EVOH) was modified with Ti-OH groups by treatments with a silane coupling agent and a titania solution. Arrangement of the Ti-OH groups on the specimen was changed into anatase by a treatment with ultra-pure water or a HCl aqueous solution. Thus surface-modified specimen formed apatite on its surface in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma within 2 d. The present surface-modification of EVOH would be useful for producing a bone substitute with bone-bonding ability as well as analogous mechanical properties to those of natural bone.",

keywords = "Anatase, Apatite, Ethylene-vinyl alcohol copolymer, Simulated body fluid, Ti-OH group",

author = "Tadashi Kokubo and Ayako Oyane and Masakazu Kawashita and Masahiko Minoda and Takeaki Miyamoto and Takashi Nakamura",

year = "2002",

month = jan,

day = "1",

language = "English",

volume = "218-220",

pages = "617--620",

journal = "Key Engineering Materials",

issn = "1013-9826",

publisher = "Trans Tech Publications",

note = "14th International Symposium on Ceramics in Medicine-Annual Meeting of the International Society for Ceramics in Medicine BIOCERAMICS'01 (ISCM) ; Conference date: 14-11-2001 Through 17-11-2001",

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TY - JOUR

T1 - Apatite-forming ability of ethylene-vinyl alcohol copolymer modified with Ti-OH groups

AU - Kokubo, Tadashi

AU - Oyane, Ayako

AU - Kawashita, Masakazu

AU - Minoda, Masahiko

AU - Miyamoto, Takeaki

AU - Nakamura, Takashi

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The surface of ethylene-vinyl alcohol copolymer (EVOH) was modified with Ti-OH groups by treatments with a silane coupling agent and a titania solution. Arrangement of the Ti-OH groups on the specimen was changed into anatase by a treatment with ultra-pure water or a HCl aqueous solution. Thus surface-modified specimen formed apatite on its surface in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma within 2 d. The present surface-modification of EVOH would be useful for producing a bone substitute with bone-bonding ability as well as analogous mechanical properties to those of natural bone.

AB - The surface of ethylene-vinyl alcohol copolymer (EVOH) was modified with Ti-OH groups by treatments with a silane coupling agent and a titania solution. Arrangement of the Ti-OH groups on the specimen was changed into anatase by a treatment with ultra-pure water or a HCl aqueous solution. Thus surface-modified specimen formed apatite on its surface in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma within 2 d. The present surface-modification of EVOH would be useful for producing a bone substitute with bone-bonding ability as well as analogous mechanical properties to those of natural bone.

KW - Anatase

KW - Apatite

KW - Ethylene-vinyl alcohol copolymer

KW - Simulated body fluid

KW - Ti-OH group

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M3 - Conference article

AN - SCOPUS:0036169440

VL - 218-220

SP - 617

EP - 620

JO - Key Engineering Materials

JF - Key Engineering Materials

SN - 1013-9826

T2 - 14th International Symposium on Ceramics in Medicine-Annual Meeting of the International Society for Ceramics in Medicine BIOCERAMICS'01 (ISCM)

Y2 - 14 November 2001 through 17 November 2001

ER -