Apatite-forming ability and mechanical properties of PTMO-modified CaO-SiO2 hybrids prepared by sol-gel processing: Effect of CaO and PTMO contents

Noboru Miyata, Ken Ichi Fuke, Qi Chen, Masakazu Kawashita, Tadashi Kokubo, Takashi Nakamura

Research output: Contribution to journalArticle

65 Citations (Scopus)

Abstract

Transparent monolithics of triethoxysilane end-capped poly(tetramethylene oxide) (Si-PTMO)-modified CaO-SiO2 hybrids were successfully synthesized by hydrolysis and polycondensation of Si-PTMO, tetraethoxysilane (TEOS) and calcium nitrate. As for the samples with varying (Ca(NO3)2)/(TEOS) molar ratios under constant ratio of (Si-PTMO)/(TEOS) of 2/3 in weight, the apatite-forming ability in a simulated body fluid (SBF) which is indicative of bioactivity, remarkably increased with increasing CaO content, although the tensile strength and Young's modulus decreased. The hybrid with (Ca(NO3)2)/(TEOS)=0.15 in mol formed an apatite on its surface within only 1 day. For this series of samples, the strain at failure which is a measure of capability for deformation of material, was found to be about 30% and almost independent of CaO content. As for the samples with varying (Si-PTMO)/(TEOS) weight ratios under constant ratio of (Ca(NO3)2)/(TEOS) of 0.15 in mol, the strain at failure increased with increasing Si-PTMO content, but the apatite-forming ability, tensile strength and Young's modulus decreased. Thus, the synthesis of the hybrids exhibiting both high apatite-forming ability and high extensibility can be achieved by selecting suitable CaO and Si-PTMO contents. These new kind of hybrid materials may be useful as bioactive bone-repairing materials.

Original languageEnglish
Pages (from-to)3033-3040
Number of pages8
JournalBiomaterials
Volume23
Issue number14
DOIs
Publication statusPublished - 2002 May 21

Keywords

  • Apatite-forming ability
  • Bioactivity
  • Mechanical properties
  • Organic-inorganic hybrids
  • Poly(tetramethylene oxide)

ASJC Scopus subject areas

  • Bioengineering
  • Ceramics and Composites
  • Biophysics
  • Biomaterials
  • Mechanics of Materials

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