Apatite formation on non-woven fabric of carboxymethylated chitin in SBF

Tadashi Kokubo, Masayuki Hanakawa, Masakazu Kawashita, Masahiko Minoda, Toshiyuki Beppu, Takeaki Miyamoto, Takashi Nakamura

Research output: Contribution to journalArticlepeer-review

79 Citations (Scopus)


Chitin fibres constituting a non-woven fabric were carboxymethylated in monochloro acetic acid and treated with saturated Ca(OH)2 aqueous solution. Within 3 days in a simulated body fluid with pH value and ion concentrations nearly equal to those of human blood plasma, a bonelike apatite layer formed on the surface of fibres of the treated fabric. The apatite-chitin fibre composite thus prepared is expected to be useful as a flexible bioactive bone-repairing material.

Original languageEnglish
Pages (from-to)4485-4488
Number of pages4
Issue number18
Publication statusPublished - 2004 Aug


  • Apatite
  • Biomimetic process
  • Carboxyl groups
  • Carboxymethylated chitin
  • Non-woven fabric
  • Simulated body fluid

ASJC Scopus subject areas

  • Bioengineering
  • Ceramics and Composites
  • Biophysics
  • Biomaterials
  • Mechanics of Materials


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