Apatite formation on non-woven fabric of carboxymethylated chitin in SBF

Tadashi Kokubo, Masayuki Hanakawa, Masakazu Kawashita, Masahiko Minoda, Toshiyuki Beppu, Takeaki Miyamoto, Takashi Nakamura

Research output: Contribution to journalArticle

78 Citations (Scopus)

Abstract

Chitin fibres constituting a non-woven fabric were carboxymethylated in monochloro acetic acid and treated with saturated Ca(OH)2 aqueous solution. Within 3 days in a simulated body fluid with pH value and ion concentrations nearly equal to those of human blood plasma, a bonelike apatite layer formed on the surface of fibres of the treated fabric. The apatite-chitin fibre composite thus prepared is expected to be useful as a flexible bioactive bone-repairing material.

Original languageEnglish
Pages (from-to)4485-4488
Number of pages4
JournalBiomaterials
Volume25
Issue number18
DOIs
Publication statusPublished - 2004 Aug 1

Keywords

  • Apatite
  • Biomimetic process
  • Carboxyl groups
  • Carboxymethylated chitin
  • Non-woven fabric
  • Simulated body fluid

ASJC Scopus subject areas

  • Bioengineering
  • Ceramics and Composites
  • Biophysics
  • Biomaterials
  • Mechanics of Materials

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  • Cite this

    Kokubo, T., Hanakawa, M., Kawashita, M., Minoda, M., Beppu, T., Miyamoto, T., & Nakamura, T. (2004). Apatite formation on non-woven fabric of carboxymethylated chitin in SBF. Biomaterials, 25(18), 4485-4488. https://doi.org/10.1016/j.biomaterials.2003.11.007