Abstract
An apatite-organic polymer hybrid is expected as a novel material for medical application, because it shows high biological affinity and high flexibility. In order to fabricate this type of hybrid, a biomimetic process was proposed, in which a bone-like apatite layer can be coated onto organic substrates by using a simulated body fluid (SBF) at ambient conditions. Potential of induction of heterogeneous nucleation of apatite on substrate materials is an important parameter to achieve a successful coating of apatite. Recently, it was reported that sericin, a protein existing on the surface of raw silk fiber, showed apatite-forming ability in 1.5 SBF which has 1.5 times the ion concentrations of SBF. In the present study, the structural effect of sericin on its apatite-forming ability was investigated in 1.5SBF. Apatite was deposited on sericin with high molecular weight and β-sheet structure in 1.5SBF after 7 days.
Original language | English |
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Pages (from-to) | 403-406 |
Number of pages | 4 |
Journal | Key Engineering Materials |
Volume | 254-256 |
Publication status | Published - 2004 Jan 1 |
Externally published | Yes |
Event | The Annual Meeting of the International Society for Ceramics in Medicine - Porto, Portugal Duration: 2003 Nov 6 → 2003 Nov 9 |
Keywords
- Biomimetic process
- Hydroxyapatite
- Sericin
- Simulated body fluid
ASJC Scopus subject areas
- Materials Science(all)
- Mechanics of Materials
- Mechanical Engineering