TY - JOUR
T1 - Antimicrobial intervention by photoirradiation of grape pomace extracts via hydroxyl radical generation
AU - Niwano, Yoshimi
AU - Tada, Mika
AU - Tsukada, Mana
N1 - Funding Information:
This study was supported by JSPS KAKENHI Grant-in-Aid for Scientific Research (C), 17K07788, 2017, and Mext-supported program for the strategic research foundation at private universities, Japan, S1312001, 2013.
Publisher Copyright:
© 2017 Niwano, Tada and Tsukada.
PY - 2017/9/21
Y1 - 2017/9/21
N2 - The annual production of grape worldwide amounts to almost 70 million tons, and around 80% is used for winemaking. The two major wastes from winemaking process, pomace and lees account for 20 and 7% of the grapes, respectively. They have been expected as a valuable resource to be recycled because they are rich in polyphenols. Polyphenols possess prooxidatve activity as well as antioxidative one just like a two sides of a coin. A typical example of the prooxidative activity is antibacterial activity of catechins. The activity is exerted through oxidation of phenolic hydroxyl moiety coulpled with reduction of dissolved oxygen leading to hydrogen peroxide (H2O2) generation. In addition, once the oxidation of phenolic hydroxyl moiety is augmented by photoirradiation, highly reactive hydroxyl radical (·OH) is generated. Accordingly, there have been several reports showing that photoirardiation of polyphenols exerts bactericidal activity via ·OH generation. This review focuses mainly on antimicrobial intervention by photoirradiation of grape pomace extract in relation to ·OH generation analyzed by an electron spin resonance-spin trapping method.
AB - The annual production of grape worldwide amounts to almost 70 million tons, and around 80% is used for winemaking. The two major wastes from winemaking process, pomace and lees account for 20 and 7% of the grapes, respectively. They have been expected as a valuable resource to be recycled because they are rich in polyphenols. Polyphenols possess prooxidatve activity as well as antioxidative one just like a two sides of a coin. A typical example of the prooxidative activity is antibacterial activity of catechins. The activity is exerted through oxidation of phenolic hydroxyl moiety coulpled with reduction of dissolved oxygen leading to hydrogen peroxide (H2O2) generation. In addition, once the oxidation of phenolic hydroxyl moiety is augmented by photoirradiation, highly reactive hydroxyl radical (·OH) is generated. Accordingly, there have been several reports showing that photoirardiation of polyphenols exerts bactericidal activity via ·OH generation. This review focuses mainly on antimicrobial intervention by photoirradiation of grape pomace extract in relation to ·OH generation analyzed by an electron spin resonance-spin trapping method.
KW - Electron spin resonance
KW - Grape pomace
KW - Hydroxyl radical
KW - Photooxidation of polyphenol
KW - Spin trapping
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U2 - 10.3389/fphys.2017.00728
DO - 10.3389/fphys.2017.00728
M3 - Short survey
AN - SCOPUS:85029686444
VL - 8
JO - Frontiers in Physiology
JF - Frontiers in Physiology
SN - 1664-042X
IS - SEP
M1 - 728
ER -