TY - JOUR
T1 - Antigen detection in the murine models of systemic candidiasis
AU - Mitsutake, K.
AU - Kohno, S.
AU - Matsuda, H.
AU - Yoshitomi, Y.
AU - Miyazaki, Y.
AU - Higashiyama, Y.
AU - Tanaka, K.
AU - Iwamoto, M.
AU - Maesaki, S.
AU - Kaku, M.
N1 - Copyright:
This record is sourced from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PY - 1992/6
Y1 - 1992/6
N2 - We compared two latex agglutination tests for serum candidal antigen in murine models of systemic infection and gastrointestinal colonization. In the intravascular-infection model, mannan detection test was positive at 2 hours after inoculation, but Cand-Tec was less sensitive than mannan detection test in this model. In the gastrointestinal colonization model followed by systemic infection in neutropenic mice, the mannan antigen test became positive after 3 weeks of colonization with increased number of Candida of the stool, and Cand-Tec became positive after 5 weeks in neutropenic mice.
AB - We compared two latex agglutination tests for serum candidal antigen in murine models of systemic infection and gastrointestinal colonization. In the intravascular-infection model, mannan detection test was positive at 2 hours after inoculation, but Cand-Tec was less sensitive than mannan detection test in this model. In the gastrointestinal colonization model followed by systemic infection in neutropenic mice, the mannan antigen test became positive after 3 weeks of colonization with increased number of Candida of the stool, and Cand-Tec became positive after 5 weeks in neutropenic mice.
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U2 - 10.11150/kansenshogakuzasshi1970.66.716
DO - 10.11150/kansenshogakuzasshi1970.66.716
M3 - Article
C2 - 1431353
AN - SCOPUS:0026882901
VL - 66
SP - 716
EP - 720
JO - Nippon Densenbyo Gakkai zasshi
JF - Nippon Densenbyo Gakkai zasshi
SN - 0387-5911
IS - 6
ER -