Antidepressant Principles of Valeriana fauriei Roots

Yoshiteru Oshima, Setsu Matsuoka, Yasushi Ohizumi

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

A methanol extract of the roots of Valeriana fauriei (Valerianaceae), exhibited antidepressant activity in mice. The extract was fractionated, monitored by the activity, to afford a-kessyl alcohol as an active principle. The antidepressant activity of some guaiane and valerane types of sesquiterpenoids in the active fraction was also evaluated.

Original languageEnglish
Pages (from-to)169-170
Number of pages2
JournalChemical and Pharmaceutical Bulletin
Volume43
Issue number1
DOIs
Publication statusPublished - 1995

Keywords

  • Valeriana fauriei root
  • antidepressant activity
  • guaiane
  • valerane
  • α-kessyl alcohol

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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