Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

Tomohito Kameda; Masahiko Ono; Guido Grause; Tadaaki Mizoguchi; Toshiaki Yoshioka

doi:10.1007/s10965-010-9492-3

Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

Tomohito Kameda, Masahiko Ono, Guido Grause, Tadaaki Mizoguchi, Toshiaki Yoshioka

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

Original language	English
Pages (from-to)	945-947
Number of pages	3
Journal	Journal of Polymer Research
Volume	18
Issue number	5
DOIs	https://doi.org/10.1007/s10965-010-9492-3
Publication status	Published - 2011 Sep

Keywords

Bacterial adhesion
Nucleophilic substitution: Thiocyanate
Poly(vinyl chloride)

ASJC Scopus subject areas

Polymers and Plastics
Organic Chemistry
Materials Chemistry

Access to Document

10.1007/s10965-010-9492-3

Fingerprint Dive into the research topics of 'Antibacterial effect of thiocyanate substituted poly(vinyl chloride)'. Together they form a unique fingerprint.

Cite this

@article{089bdd57915e4d7bb43d3b85f828608f,

title = "Antibacterial effect of thiocyanate substituted poly(vinyl chloride)",

abstract = "Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.",

keywords = "Bacterial adhesion, Nucleophilic substitution: Thiocyanate, Poly(vinyl chloride)",

author = "Tomohito Kameda and Masahiko Ono and Guido Grause and Tadaaki Mizoguchi and Toshiaki Yoshioka",

year = "2011",

month = sep,

doi = "10.1007/s10965-010-9492-3",

language = "English",

volume = "18",

pages = "945--947",

journal = "Journal of Polymer Research",

issn = "1022-9760",

publisher = "Springer Netherlands",

number = "5",

}

TY - JOUR

T1 - Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

AU - Kameda, Tomohito

AU - Ono, Masahiko

AU - Grause, Guido

AU - Mizoguchi, Tadaaki

AU - Yoshioka, Toshiaki

PY - 2011/9

Y1 - 2011/9

N2 - Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

AB - Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

KW - Bacterial adhesion

KW - Nucleophilic substitution: Thiocyanate

KW - Poly(vinyl chloride)

UR - http://www.scopus.com/inward/record.url?scp=80053385981&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80053385981&partnerID=8YFLogxK

U2 - 10.1007/s10965-010-9492-3

DO - 10.1007/s10965-010-9492-3

M3 - Article

AN - SCOPUS:80053385981

VL - 18

SP - 945

EP - 947

JO - Journal of Polymer Research

JF - Journal of Polymer Research

SN - 1022-9760

IS - 5

ER -

Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this