Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

Tomohito Kameda; Masahiko Ono; Guido Grause; Tadaaki Mizoguchi; Toshiaki Yoshioka

doi:10.1007/s10965-010-9492-3

Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

Tomohito Kameda, Masahiko Ono, Guido Grause, Tadaaki Mizoguchi, Toshiaki Yoshioka

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

Original language	English
Pages (from-to)	945-947
Number of pages	3
Journal	Journal of Polymer Research
Volume	18
Issue number	5
DOIs	https://doi.org/10.1007/s10965-010-9492-3
Publication status	Published - 2011 Sep

Keywords

Bacterial adhesion
Nucleophilic substitution: Thiocyanate
Poly(vinyl chloride)

ASJC Scopus subject areas

Polymers and Plastics
Organic Chemistry
Materials Chemistry

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10.1007/s10965-010-9492-3

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abstract = "Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.",

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author = "Tomohito Kameda and Masahiko Ono and Guido Grause and Tadaaki Mizoguchi and Toshiaki Yoshioka",

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T1 - Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

AU - Kameda, Tomohito

AU - Ono, Masahiko

AU - Grause, Guido

AU - Mizoguchi, Tadaaki

AU - Yoshioka, Toshiaki

PY - 2011/9

Y1 - 2011/9

N2 - Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

AB - Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

KW - Bacterial adhesion

KW - Nucleophilic substitution: Thiocyanate

KW - Poly(vinyl chloride)

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JO - Journal of Polymer Research

JF - Journal of Polymer Research

SN - 1022-9760

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ER -

Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

Abstract

Keywords

ASJC Scopus subject areas

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