Antibacterial effect of thiocyanate substituted poly(vinyl chloride)

Tomohito Kameda, Masahiko Ono, Guido Grause, Tadaaki Mizoguchi, Toshiaki Yoshioka

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)

Abstract

Poly(vinyl chloride) (PVC) modified in different solvents by nucleophilic substitution with thiocyanate was exposed to Gram-negative bacteria of the strain Staphylococcus capitis. All modified pieces reduced the adhesion of bacteria by between 67 and 79%. More important for the bacteria suppression than the substitution rate was the ratio between thiocyanate and isothiocyanate groups. The best result was obtained with PVC modified in tetrahydrofuran/ dimethylsulfoxide, containing only antibacterial active isothiocyanate groups, while inactive thiocyanate groups were absent.

Original languageEnglish
Pages (from-to)945-947
Number of pages3
JournalJournal of Polymer Research
Volume18
Issue number5
DOIs
Publication statusPublished - 2011 Sep

Keywords

  • Bacterial adhesion
  • Nucleophilic substitution: Thiocyanate
  • Poly(vinyl chloride)

ASJC Scopus subject areas

  • Polymers and Plastics
  • Organic Chemistry
  • Materials Chemistry

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