Anti-myelin oligodendrocyte glycoprotein antibodies in a patient with recurrent optic neuritis involving the cerebral white matter and brainstem

Tadashi Adachi, Kenichi Yasui, Toshiyuki Takahashi, Kazuo Fujihara, Yasuhiro Watanabe, Kenji Nakashima

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We herein report a case of recurrent optic neuritis involving the cerebral white matter and brainstem in a patient positive for anti-myelin oligodendrocyte glycoprotein (MOG) antibodies. The patient had an initial attack at 24 years of age. Optic neuritis recurred over 14 years, and she was admitted to our neurology unit at 38 years of age. She showed bilateral optic neuritis, high-intensity lesions in the cerebral white matter and brainstem on T2 MRI with contrast enhancement, and elevated serum anti-MOG antibodies. Immunotherapy improved the MRI lesions. Recurrent optic neuritis in patients with anti-MOG antibodies may thus involve the cerebral white matter and brainstem.

Original languageEnglish
Pages (from-to)1351-1354
Number of pages4
JournalInternal Medicine
Volume55
Issue number10
DOIs
Publication statusPublished - 2016 Jan 1

Keywords

  • Brainstem
  • MOG
  • MRI
  • NMO
  • White matter

ASJC Scopus subject areas

  • Internal Medicine

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