Annual dynamics of marine birnavirus (MABV) in cultured Japanese flounder Paralichthys olivaceus and sea water

Manami Inaba, Takeshi Kimura, Rika Kikukawa, Mitsuko Iwasaki, Masato Nose, Satoru Suzuki

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Seasonal changes in the infection state of marine birnavirus (MABV) in Japanese flounder Paralichthys olivaceus and in rearing sea water are described. Sea water and 10-11 healthy fish were sampled monthly from April 2002 to February 2003. The MABV genome was detected throughout the year in >80% of the fish examined at each sampling. The virus was isolated from the liver, kidney, and spleen, but not from the brain. The detection rate in each organ increased from April to October, and then decreased. Detection of virus antigen by the indirect fluorescent antibody technique also showed that the virus was present from spring to autumn (June-September) in the liver, kidney, and spleen, but not the brain. Sequence analysis of the MABV genome at the VP2-NS region revealed two specific mutations compared to the standard yellowtail strain (Y-6). It is suggested that the infection state of MABV in Japanese flounder changes to a latent or persistent infection after autumn. MABV was detected in sea water between September and February, suggesting that virus particles in the environment are relatively higher during cool seasons.

Original languageEnglish
Pages (from-to)615-622
Number of pages8
JournalFisheries Science
Volume73
Issue number3
DOIs
Publication statusPublished - 2007 Jun
Externally publishedYes

Keywords

  • Aquabirnavirus
  • Flounder
  • Marine birnavirus
  • Sea water
  • Seasonal change

ASJC Scopus subject areas

  • Aquatic Science

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