Angiotensin i-converting enzyme inhibitors in autolysates of squid liver and mantle muscle

Yutaka Wako, Satoru Ishikawa, Koji Muramoto

    Research output: Contribution to journalArticlepeer-review

    21 Citations (Scopus)

    Abstract

    Autolysis of squid liver and mantle muscle homogenates, and blends of both, each yielded inhibitory activity toward the angiotensin I-converting enzyme. The inhibitory activity and the amount of solubilized protein in each of these autolysates were examined over a period of 24 h. Inhibitory peptides were isolated from the mixed autolysate, their structures (IC50) being Tyr-Ala-Leu-Pro-His-Ala (9.8μ m) and Gly-Tyr-Ala-Leu-Pro-His-Ala (27.3 μ m).

    Original languageEnglish
    Pages (from-to)1353-1355
    Number of pages3
    JournalBioscience, Biotechnology and Biochemistry
    Volume60
    Issue number8
    DOIs
    Publication statusPublished - 1996 Jan

    Keywords

    • Angiotensin-converting enzyme inhibitor
    • Liver
    • Mantle muscle
    • Squid

    ASJC Scopus subject areas

    • Biotechnology
    • Analytical Chemistry
    • Biochemistry
    • Applied Microbiology and Biotechnology
    • Molecular Biology
    • Organic Chemistry

    Fingerprint Dive into the research topics of 'Angiotensin i-converting enzyme inhibitors in autolysates of squid liver and mantle muscle'. Together they form a unique fingerprint.

    Cite this