TY - JOUR
T1 - Analysis of temperature rise induced by high-intensity focused ultrasound in tissue-mimicking gel considering cavitation bubbles
AU - Asai, Ayumu
AU - Okano, Hiroki
AU - Yoshizawa, Shin
AU - Umemura, Shin Ichiro
PY - 2013/7/1
Y1 - 2013/7/1
N2 - High-intensity focused ultrasound (HIFU) causes a selective temperature rise in tissue and is used as a noninvasive method for tumor treatment. However, there is a problem in that it typically takes several hours to treat a large tumor. The development of a highly efficient method is required to shorten the treatment time. It is known that cavitation bubbles generated by HIFU enhance HIFU heating. In this study, the enhancement of the heating effect by cavitation was estimated in a numerical simulation solving a bio-heat transfer equation (BHTE) by increasing the absorption coefficients in and out of the volume of cavitation bubbles. The absorption coefficients were obtained by a curve fitting the temperature rise near the focal point between experiment and simulation. The results show that cavitation bubbles caused the increase in ultrasonic absorption not only in but also near the volume of cavitation bubbles.
AB - High-intensity focused ultrasound (HIFU) causes a selective temperature rise in tissue and is used as a noninvasive method for tumor treatment. However, there is a problem in that it typically takes several hours to treat a large tumor. The development of a highly efficient method is required to shorten the treatment time. It is known that cavitation bubbles generated by HIFU enhance HIFU heating. In this study, the enhancement of the heating effect by cavitation was estimated in a numerical simulation solving a bio-heat transfer equation (BHTE) by increasing the absorption coefficients in and out of the volume of cavitation bubbles. The absorption coefficients were obtained by a curve fitting the temperature rise near the focal point between experiment and simulation. The results show that cavitation bubbles caused the increase in ultrasonic absorption not only in but also near the volume of cavitation bubbles.
UR - http://www.scopus.com/inward/record.url?scp=84880989099&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84880989099&partnerID=8YFLogxK
U2 - 10.7567/JJAP.52.07HF02
DO - 10.7567/JJAP.52.07HF02
M3 - Article
AN - SCOPUS:84880989099
VL - 52
JO - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes
JF - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes
SN - 0021-4922
IS - 7 PART 2
M1 - 07HF02
ER -