An unmediated hydrogen peroxide sensor based on a hemoglobin-SDS film modified electrode

C. Fan, I. Suzuki, Q. Chen, G. Li, J. I. Anzai

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

An unmediated hydrogen peroxide sensor is designed in this paper by employing a hemoglobin-SDS film modified electrode. Hemoglobin exhibits direct (unmediated) electrochemistry at the modified electrode. The protein also shows elegant catalytic activity towards the electrochemical reduction of hydrogen peroxide. Consequently, a prototype hydrogen peroxide sensor is prepared. Under optimum conditions, this sensor provides a linear response over the hydrogen peroxide concentrations in the range of 1x10-5 ~ 1 x 10-4 mol/L. The detection limit was 2 x 10-6 mol/L The relative standard deviation was 4.2% for 6 successive determinations of the hydrogen peroxide at 1xl0-5 mol/L. This configuration is shown to be sensitive, stable and easily fabricated. It might be useful in the biological and industrial fields.

Original languageEnglish
Pages (from-to)2631-2644
Number of pages14
JournalAnalytical Letters
Volume33
Issue number13
DOIs
Publication statusPublished - 2000 Jan 1

Keywords

  • Hemoglobin
  • Hydrogen peroxide sensor
  • SDS

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Spectroscopy
  • Clinical Biochemistry
  • Biochemistry, medical
  • Electrochemistry

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