An Outbreak of Legionnaires' Pneumonia in a Nursing Home

Shigefumi Maesaki; Shigeru Kohno; Hironobu Koga; Mitsuo Kaku; Yuko Yoshitomi; Hiroshi Yamada; Haruko Matsuda; Yasuhito Higashiyama; Kohei Hara; Makiko Seto; Shirou Nakaguchi; Kohci Hara

doi:10.2169/internalmedicine.31.508

An Outbreak of Legionnaires' Pneumonia in a Nursing Home

Shigefumi Maesaki, Shigeru Kohno, Hironobu Koga, Mitsuo Kaku, Yuko Yoshitomi, Hiroshi Yamada, Haruko Matsuda, Yasuhito Higashiyama, Kohei Hara, Makiko Seto, Shirou Nakaguchi, Kohci Hara

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

An outbreak of Legionnaires' pneumonia occurred at a nursing home in December 1990. A 79-year-old female and a 73-year-old male clerk who were staying at the nursing home developed pneumonia with only a 5-day interval. Legionella pneumophila serogroup I was isolated from transtracheal aspirate of the former and sputum of the latter. After treatment with a combination of erythromycin and rifampicin both patients improved. Serological surveillance of inpatients and staff of the nursing home was performed in February 1991. Seven out of 51 samples (14.0%) showed a titer higher than 1:128 of anti-Legionella pneumophila serogroup I antibody determined by indirect immunofluorecence; two of these seven complained of respiratory symptoms. Molecular epidemiology analyzed by restriction endonuclease digestion of isolated L. pneumophila showed an identical pattern which suggested a common origin.

Original language	English
Pages (from-to)	508-512
Number of pages	5
Journal	Internal Medicine
Volume	31
Issue number	4
DOIs	https://doi.org/10.2169/internalmedicine.31.508
Publication status	Published - 1992

Keywords

Legionella pneumophila serogroup I
anti-Legionella antibody titer
molecular epidemiology
transtracheal aspiration

ASJC Scopus subject areas

Internal Medicine

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An Outbreak of Legionnaires' Pneumonia in a Nursing Home. / Maesaki, Shigefumi; Kohno, Shigeru; Koga, Hironobu; Kaku, Mitsuo; Yoshitomi, Yuko; Yamada, Hiroshi; Matsuda, Haruko; Higashiyama, Yasuhito; Hara, Kohei; Seto, Makiko; Nakaguchi, Shirou; Hara, Kohci.

In: Internal Medicine, Vol. 31, No. 4, 1992, p. 508-512.

Research output: Contribution to journal › Article › peer-review

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