An Outbreak of Legionnaires' Pneumonia in a Nursing Home

Shigefumi Maesaki, Shigeru Kohno, Hironobu Koga, Mitsuo Kaku, Yuko Yoshitomi, Hiroshi Yamada, Haruko Matsuda, Yasuhito Higashiyama, Kohei Hara, Makiko Seto, Shirou Nakaguchi, Kohci Hara

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


An outbreak of Legionnaires' pneumonia occurred at a nursing home in December 1990. A 79-year-old female and a 73-year-old male clerk who were staying at the nursing home developed pneumonia with only a 5-day interval. Legionella pneumophila serogroup I was isolated from transtracheal aspirate of the former and sputum of the latter. After treatment with a combination of erythromycin and rifampicin both patients improved. Serological surveillance of inpatients and staff of the nursing home was performed in February 1991. Seven out of 51 samples (14.0%) showed a titer higher than 1:128 of anti-Legionella pneumophila serogroup I antibody determined by indirect immunofluorecence; two of these seven complained of respiratory symptoms. Molecular epidemiology analyzed by restriction endonuclease digestion of isolated L. pneumophila showed an identical pattern which suggested a common origin.

Original languageEnglish
Pages (from-to)508-512
Number of pages5
JournalInternal Medicine
Issue number4
Publication statusPublished - 1992
Externally publishedYes


  • Legionella pneumophila serogroup I
  • anti-Legionella antibody titer
  • molecular epidemiology
  • transtracheal aspiration

ASJC Scopus subject areas

  • Internal Medicine


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