TY - JOUR
T1 - An operative case of ulcerative colitis associated with hyperthyroidism
AU - Kohyama, Atsushi
AU - Funayama, Yuji
AU - Fukushima, Kouhei
AU - Shibata, Chikashi
AU - Miura, Koh
AU - Takahashi, Ken Ichi
AU - Ogawa, Hitoshi
AU - Ueno, Tatsuya
AU - Sasaki, Iwao
AU - Hiwatashi, Nobuo
PY - 2009
Y1 - 2009
N2 - We encountered a rare operative case of hyperthyroidism followed by ulcerative colitis (UC). A 26-year-old mam was referred to our department to undergo an operation. We suspected the possible complication of adrenal insufficiency, since he suffered from severe weight loss, a high fever and palpitation on admission. We diagnosed hyperthyroidism, however, based on the presence of high serum free T3 and T4 levels and a decreased TSH level. After improving the symptoms and the thyroid function by administering thiamazole, we then performed a total proctocolectomy. Although a high rate of association of autoimmune thyroid diseases with UC has been suggested, only 9 cases of hyperthyroidism coexisting with UC have so far been reported in Japan. A common immunological process has been suggested to be implicated in the pathogenesis of this association, however, the exact mechanism needs to be elucidated in the future.
AB - We encountered a rare operative case of hyperthyroidism followed by ulcerative colitis (UC). A 26-year-old mam was referred to our department to undergo an operation. We suspected the possible complication of adrenal insufficiency, since he suffered from severe weight loss, a high fever and palpitation on admission. We diagnosed hyperthyroidism, however, based on the presence of high serum free T3 and T4 levels and a decreased TSH level. After improving the symptoms and the thyroid function by administering thiamazole, we then performed a total proctocolectomy. Although a high rate of association of autoimmune thyroid diseases with UC has been suggested, only 9 cases of hyperthyroidism coexisting with UC have so far been reported in Japan. A common immunological process has been suggested to be implicated in the pathogenesis of this association, however, the exact mechanism needs to be elucidated in the future.
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M3 - Article
C2 - 19498314
AN - SCOPUS:68949151922
VL - 106
SP - 820
EP - 825
JO - Journal of Japanese Society of Gastroenterology
JF - Journal of Japanese Society of Gastroenterology
SN - 0446-6586
IS - 6
ER -