An operative case of ulcerative colitis associated with hyperthyroidism

Atsushi Kohyama, Yuji Funayama, Kouhei Fukushima, Chikashi Shibata, Koh Miura, Ken Ichi Takahashi, Hitoshi Ogawa, Tatsuya Ueno, Iwao Sasaki, Nobuo Hiwatashi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We encountered a rare operative case of hyperthyroidism followed by ulcerative colitis (UC). A 26-year-old mam was referred to our department to undergo an operation. We suspected the possible complication of adrenal insufficiency, since he suffered from severe weight loss, a high fever and palpitation on admission. We diagnosed hyperthyroidism, however, based on the presence of high serum free T3 and T4 levels and a decreased TSH level. After improving the symptoms and the thyroid function by administering thiamazole, we then performed a total proctocolectomy. Although a high rate of association of autoimmune thyroid diseases with UC has been suggested, only 9 cases of hyperthyroidism coexisting with UC have so far been reported in Japan. A common immunological process has been suggested to be implicated in the pathogenesis of this association, however, the exact mechanism needs to be elucidated in the future.

Original languageEnglish
Pages (from-to)820-825
Number of pages6
JournalJournal of Japanese Society of Gastroenterology
Volume106
Issue number6
Publication statusPublished - 2009

ASJC Scopus subject areas

  • Gastroenterology

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