An immunohistochemical study of methionine-enkephalin-Arg6-Gly7-Leu8-like immunoreactivity-containing neurons in the parasympathetic preganglionic regions of the rat spinal cord

Tooru Shimosegawa; Masaru Koizumi; Takayoshi Toyota; Yoshio Goto; Chizuko Yanaihara; Noboru Yanaihara

doi:10.1016/0006-8993(87)90804-3

An immunohistochemical study of methionine-enkephalin-Arg⁶-Gly⁷-Leu⁸-like immunoreactivity-containing neurons in the parasympathetic preganglionic regions of the rat spinal cord

Tooru Shimosegawa, Masaru Koizumi, Takayoshi Toyota, Yoshio Goto, Chizuko Yanaihara, Noboru Yanaihara

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The localization of the methionine-enkephalin-Arg⁶-Gly⁷-Leu⁸ (Met-Enk-Arg-Gly-Leu)-like immunoreactivity-containing neurons in the rat lumbosacral spinal cord was immunohistochemically examined by an antiserum very specific to Met-Enk-Arg-Gly-Leu. The immunoreactive neurons occupied the positions corresponding to the parasympathetic preganglionic nuclei determined by the previous horseradish peroxidase (HRP)-tracing experiments. The present study suggests that the parasympathetic preganglionic neurons in the rat lumbosacral spinal cord produce preproenkephalin A and its related peptides.

Original language	English
Pages (from-to)	341-347
Number of pages	7
Journal	Brain research
Volume	406
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(87)90804-3
Publication status	Published - 1987 Mar 17

Keywords

Immunohistochemistry
Met-Enk-Arg-Gly-Leu
Parasympathetic preganglionic neuron
Rat

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(87)90804-3

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An immunohistochemical study of methionine-enkephalin-Arg⁶-Gly⁷-Leu⁸-like immunoreactivity-containing neurons in the parasympathetic preganglionic regions of the rat spinal cord. / Shimosegawa, Tooru; Koizumi, Masaru; Toyota, Takayoshi; Goto, Yoshio; Yanaihara, Chizuko; Yanaihara, Noboru.

In: Brain research, Vol. 406, No. 1-2, 17.03.1987, p. 341-347.

Research output: Contribution to journal › Article › peer-review

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abstract = "The localization of the methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu)-like immunoreactivity-containing neurons in the rat lumbosacral spinal cord was immunohistochemically examined by an antiserum very specific to Met-Enk-Arg-Gly-Leu. The immunoreactive neurons occupied the positions corresponding to the parasympathetic preganglionic nuclei determined by the previous horseradish peroxidase (HRP)-tracing experiments. The present study suggests that the parasympathetic preganglionic neurons in the rat lumbosacral spinal cord produce preproenkephalin A and its related peptides.",

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