An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication

Shu Matsukawa; Yasuhiko Hashimoto; Masato Kato; Kunihiko Hoshi; Daizoh Satoh; Takashi Horinouchi; Shun Satoh; Toshio Saishu

doi:10.1620/tjem.181.467

An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication

Shu Matsukawa, Yasuhiko Hashimoto, Masato Kato, Kunihiko Hoshi, Daizoh Satoh, Takashi Horinouchi, Shun Satoh, Toshio Saishu

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Abstract

We evaluated the neuromuscular reversal with edrophonium using peripheral nerve stimulator and recorder in a patient with malathion intoxication. Edrophonium 10mg i.v. caused an increase in single twitch tension by 76% of the control during the recovery phase from an acute cholinergic crisis 16 days after ingestion of malathion solution. The present study indicated that edrophonium test seems to be a reliable monitoring in evaluating neuromuscular reversal in the patient with acute malathion insecticide poisoning.

Original language	English
Pages (from-to)	467-469
Number of pages	3
Journal	Tohoku Journal of Experimental Medicine
Volume	181
Issue number	4
DOIs	https://doi.org/10.1620/tjem.181.467
Publication status	Published - 1997 Apr

Keywords

Cholinergic crisis
Edrophonium
Malathion intoxication
Neuromuscular reversal

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1620/tjem.181.467

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An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication. / Matsukawa, Shu; Hashimoto, Yasuhiko; Kato, Masato; Hoshi, Kunihiko; Satoh, Daizoh; Horinouchi, Takashi; Satoh, Shun; Saishu, Toshio.

In: Tohoku Journal of Experimental Medicine, Vol. 181, No. 4, 04.1997, p. 467-469.

Research output: Contribution to journal › Article › peer-review

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AU - Satoh, Shun

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An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication

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