An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication

Shu Matsukawa, Yasuhiko Hashimoto, Masato Kato, Kunihiko Hoshi, Daizoh Satoh, Takashi Horinouchi, Shun Satoh, Toshio Saishu

Research output: Contribution to journalArticlepeer-review

Abstract

We evaluated the neuromuscular reversal with edrophonium using peripheral nerve stimulator and recorder in a patient with malathion intoxication. Edrophonium 10mg i.v. caused an increase in single twitch tension by 76% of the control during the recovery phase from an acute cholinergic crisis 16 days after ingestion of malathion solution. The present study indicated that edrophonium test seems to be a reliable monitoring in evaluating neuromuscular reversal in the patient with acute malathion insecticide poisoning.

Original languageEnglish
Pages (from-to)467-469
Number of pages3
JournalTohoku Journal of Experimental Medicine
Volume181
Issue number4
DOIs
Publication statusPublished - 1997 Apr

Keywords

  • Cholinergic crisis
  • Edrophonium
  • Malathion intoxication
  • Neuromuscular reversal

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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