Abstract
An extremely practical method for synthesis of sugar orthoesters has been developed without using any organic amines or heavy metals as additives. Various sugar orthoesters were prepared in good yields by the reaction of an acylated glycosyl bromide and an alcohol in the presence of potassium fluoride.
Original language | English |
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Pages (from-to) | 8847-8848 |
Number of pages | 2 |
Journal | Tetrahedron Letters |
Volume | 45 |
Issue number | 48 |
DOIs | |
Publication status | Published - 2004 Nov 22 |
Keywords
- Glycosyl bromides
- Potassium fluoride
- Sugar orthoesters
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry