An environmentally benign and practical synthesis of sugar orthoesters promoted by potassium fluoride

Shinichiro Shoda, Masashi Moteki, Ryuko Izumi, Masato Noguchi

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

An extremely practical method for synthesis of sugar orthoesters has been developed without using any organic amines or heavy metals as additives. Various sugar orthoesters were prepared in good yields by the reaction of an acylated glycosyl bromide and an alcohol in the presence of potassium fluoride.

Original languageEnglish
Pages (from-to)8847-8848
Number of pages2
JournalTetrahedron Letters
Volume45
Issue number48
DOIs
Publication statusPublished - 2004 Nov 22

Keywords

  • Glycosyl bromides
  • Potassium fluoride
  • Sugar orthoesters

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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