Abstract
An enantio- and stereocontrolled route to epopromycin B having the epoxy-β-aminoketone pharmacophore is developed based on the cinchona alkaloid-catalyzed Baylis-Hillman reaction of N-Fmoc-leucinal.
Original language | English |
---|---|
Pages (from-to) | 7867-7871 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 42 |
Issue number | 44 |
DOIs | |
Publication status | Published - 2001 Oct 29 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry