Abstract
An enantio- and stereocontrolled route to epopromycin B having the epoxy-β-aminoketone pharmacophore is developed based on the cinchona alkaloid-catalyzed Baylis-Hillman reaction of N-Fmoc-leucinal.
| Original language | English |
|---|---|
| Pages (from-to) | 7867-7871 |
| Number of pages | 5 |
| Journal | Tetrahedron Letters |
| Volume | 42 |
| Issue number | 44 |
| DOIs | |
| Publication status | Published - 2001 Oct 29 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry
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Cite this
Iwabuchi, Y., Sugihara, T., Esumi, T., & Hatakeyama, S. (2001). An enantio- and stereocontrolled route to epopromycin B via cinchona alkaloid-catalyzed Baylis-Hillman reaction. Tetrahedron Letters, 42(44), 7867-7871. https://doi.org/10.1016/S0040-4039(01)01676-8