Abstract
An efficient strategy for the synthesis of 2,6-disubstituted 2,3-dihydro-4H-pyran-4-ones has been developed, which relied on Sonogashira coupling of alkynes and p-toluenethiol esters and AgOTf-promoted 6-endo-dig cyclization of the derived -hydroxy ynones.
Original language | English |
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Article number | U01010ST |
Pages (from-to) | 1239-1242 |
Number of pages | 4 |
Journal | Synlett |
Issue number | 8 |
DOIs | |
Publication status | Published - 2010 May 14 |
Keywords
- Cross-coupling
- Cyclization
- Dihydropyrans
- Heterocycles
- Palladium
ASJC Scopus subject areas
- Organic Chemistry