Abstract
A rapid chemical synthesis of 2‐[carbonyl‐11C]acetamido‐2‐deoxy‐D‐glucopyranose (N‐[carbonyl‐11C]acetyl‐D‐glucosamine) starting from [11C]carbon dioxide is described. The total time required for the synthesis, the radiochemical yield, and purity of the titled sugar are ca. 60 min, 49.5% (based on [carbonyl‐11C]acetic acid), and >98%, respectively.
Original language | English |
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Pages (from-to) | 485-490 |
Number of pages | 6 |
Journal | Journal of Labelled Compounds and Radiopharmaceuticals |
Volume | 29 |
Issue number | 4 |
DOIs |
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Publication status | Published - 1991 Apr |
Keywords
- 2‐[carbonyl‐C]Acetamido‐2‐deoxy‐D‐glucopyranose
- N[carbonyl‐C]acetyl‐D‐glucosamine, [C]carbon dioxide
- [carbonyl‐C]acetic acid
- chemical synthesis
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Radiology Nuclear Medicine and imaging
- Drug Discovery
- Spectroscopy
- Organic Chemistry