An efficient synthesis of 2‐ [ carbonyl‐ 11C]acetamido‐2‐deoxy‐D‐glucopyranose (N‐[carbonyl‐11C]acetyl‐D‐glucosamine)

Masao Tada, Atsushi Oikawa, Ren Iwata, Kazunori Sato, Hiroshi Sugiyama, Kazuo Kubota, Kiichi Ishiwata, Hiromu Takahashi, Akira Wakui, Yoshinao Abe, Tatsuo Yamaguchi, Takehiko Fujiwara, Tachio Sato, Tatsuo Ido

    Research output: Contribution to journalComment/debatepeer-review

    1 Citation (Scopus)


    A rapid chemical synthesis of 2‐[carbonyl‐11C]acetamido‐2‐deoxy‐D‐glucopyranose (N‐[carbonyl‐11C]acetyl‐D‐glucosamine) starting from [11C]carbon dioxide is described. The total time required for the synthesis, the radiochemical yield, and purity of the titled sugar are ca. 60 min, 49.5% (based on [carbonyl‐11C]acetic acid), and >98%, respectively.

    Original languageEnglish
    Pages (from-to)485-490
    Number of pages6
    JournalJournal of Labelled Compounds and Radiopharmaceuticals
    Issue number4
    Publication statusPublished - 1991 Apr


    • 2‐[carbonyl‐C]Acetamido‐2‐deoxy‐D‐glucopyranose
    • N[carbonyl‐C]acetyl‐D‐glucosamine, [C]carbon dioxide
    • [carbonyl‐C]acetic acid
    • chemical synthesis

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Biochemistry
    • Radiology Nuclear Medicine and imaging
    • Drug Discovery
    • Spectroscopy
    • Organic Chemistry


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