An efficient surface modification for selective control of cell attachement using photochemical reaction

Kihoon Jang, Kae Sato, Tomohiro Konno, Kazuhiko Ishihara, Takehiko Kitamori

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

In this paper, we employed photochemical reaction for controlling the cell adhesion on the glass surface. The strategy is based on combining 2-Methacryloyloxyethyl phosphorylcholine (MPC) which is known to reduce non-specific binding, and photolabile linker (PL) for selective cell patterning. The MPC modified surface was irradiated through the MASK by UV and MPC were removed. After selective MPC cleavage, the cells only attached on UV illuminated region, which showed the selective surface control of cell attachment was performed using photochemical reaction.

Original languageEnglish
Title of host publicationProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
EditorsJean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
PublisherChemical and Biological Microsystems Society
Pages1628-1630
Number of pages3
ISBN (Electronic)9780979806407
Publication statusPublished - 2007
Event11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France
Duration: 2007 Oct 72007 Oct 11

Publication series

NameProceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
CountryFrance
CityParis
Period07/10/707/10/11

Keywords

  • Adhesion
  • MPC
  • Photochemical
  • PL

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Jang, K., Sato, K., Konno, T., Ishihara, K., & Kitamori, T. (2007). An efficient surface modification for selective control of cell attachement using photochemical reaction. In J-L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 1628-1630). (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007). Chemical and Biological Microsystems Society.