An efficient strategy for the synthesis of endocyclic enol ethers and its application to the synthesis of spiroacetals

Haruhiko Fuwa; Makoto Sasaki

doi:10.1021/ol800815t

An efficient strategy for the synthesis of endocyclic enol ethers and its application to the synthesis of spiroacetals

Haruhiko Fuwa, Makoto Sasaki

LIF - Molecular and Chemical Life Science

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

(Chemical Equation Presented) An efficient strategy for the synthesis of endocyclic enol ethers based on a Suzuki-Miyaura coupling/ring-closing metathesis sequence has been developed. The strategy has successfully been applied to the synthesis of spiroacetals, including cytotoxic marine metabolites attenols A and B.

Original language	English
Pages (from-to)	2549-2552
Number of pages	4
Journal	Organic letters
Volume	10
Issue number	12
DOIs	https://doi.org/10.1021/ol800815t
Publication status	Published - 2008 Dec 1

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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abstract = "(Chemical Equation Presented) An efficient strategy for the synthesis of endocyclic enol ethers based on a Suzuki-Miyaura coupling/ring-closing metathesis sequence has been developed. The strategy has successfully been applied to the synthesis of spiroacetals, including cytotoxic marine metabolites attenols A and B.",

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