An efficient method for the alkynylation of oxiranes using alkynyl boranes

Masahiko Yamaguchi, Ichiro Hirao

Research output: Contribution to journalArticle

463 Citations (Scopus)

Abstract

Alkynyl boranes, generated in situ from lithium acetylides and boron trifluoride etherate, were found to react with oxiranes under mild reaction conditions to afford β-hydroxyacetylenes in high yields.

Original languageEnglish
Pages (from-to)391-394
Number of pages4
JournalTetrahedron Letters
Volume24
Issue number4
DOIs
Publication statusPublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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