Abstract
Thermal double cyclization reaction using ortho-vinylbenzaldehyde and 3-aminopropanols proceeded smoothly to give isoquinoline derivatives via 6π-azaelectrocyclization pathway. The method was applied to the efficient synthesis of (S)-cryptostyline II.
Original language | English |
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Pages (from-to) | 2722-2725 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 49 |
Issue number | 17 |
DOIs | |
Publication status | Published - 2008 Apr 21 |
Keywords
- (S)-Cryptostyline II
- 6π-Azaelectrocyclization
- Double cyclization process
- Tetrahydroisoquinoline
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry