An efficient and stereocontrolled synthesis of the nephritogenoside core structure

Makoto Sasaki, Kazuo Tachibana, Hiroshi Nakanishi

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

An efficient and stereocontrolled synthesis of the core trisaccharide 2 of nephritogenic glycopeptide, nephritogenoside 1 is described. Key to our synthetic strategy was β-selective glycosylation without neighboring group participation.

Original languageEnglish
Pages (from-to)6873-6876
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number47
DOIs
Publication statusPublished - 1991 Nov 18
Externally publishedYes

Keywords

  • glomerulonephritis
  • glycopeptide
  • nephritogenoside
  • α-nitrilium ion
  • β-selective glycosylation

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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