An efficient and regioselective iodination of electron-rich aromatic compounds using N-chlorosuccinimide and sodium iodide

Takuya Yamamoto, Kozo Toyota, Noboru Morita

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

An efficient and regioselective method for iodination of electron-rich aromatic compounds was found using N-chlorosuccinimide and sodium iodide in AcOH with short reaction times. This method is also applicable to non-benzenoid aromatic or heteroaromatic compounds.

Original languageEnglish
Pages (from-to)1364-1366
Number of pages3
JournalTetrahedron Letters
Volume51
Issue number10
DOIs
Publication statusPublished - 2010 Mar 10

Keywords

  • Aromatic compounds
  • Electrophilic substitution
  • Iodination
  • Thiophenes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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