An autopsy case of AIDS with hemophilia A who died of DIC and gastrointestinal bleeding associated with gastric carcinoma (signet ring cell carcinoma)

M. Ishikawa, S. Suzuki, Y. Akutu, T. Toyota, M. Nose, H. Sakai, K. Mori

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6 Citations (Scopus)

Abstract

We describe a 39 years-old male hemophilia A patient with acquired immunodeficiency syndrome (AIDS) developing to disseminated intravascular coagulation (DIC) due to gastric carcinoma. He had been diagnosed as human immunodeficiency virus (HIV) sero-positive in 1990. Since then, he has been treated by the oral administration of zidovudine (AZT), dideoxyinosine (ddI) and intravenous administration of glycyrrhizin. In September 1990, he suddenly complained abdominal pain with bloody stool. His condition deteriorated in spite of our intensive treatment for DIC. He died of multiple organ failure (MOF) due to DIC. The autopsy findings showed gastric carcinoma, defined of signet ring cell carcinoma histopathologically. But neither opportunistic infection nor other cause of DIC were observed.

Original languageEnglish
Pages (from-to)886-891
Number of pages6
Journal[Rinshō ketsueki] The Japanese journal of clinical hematology
Volume35
Issue number9
Publication statusPublished - 1994 Sep

ASJC Scopus subject areas

  • Medicine(all)

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