An autopsied case of neuromyelitis optica with a large cavitary cerebral lesion

M. Nakamura, M. Endo, K. Murakami, H. Konno, Kazuo Fujihara, Y. Itoyama

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

We report a case of neuromyelitis optica (NMO) with a large cerebral lesion. The patient had an episode of fever and consciousness disturbance with a tumefactive frontal white matter lesion at age 43, and then repeated bilateral optic neuritis and transverse myelitis until she died at age 63. Histopathological examinations revealed that marked tissue destruction, cavities and inflammatory changes typical of NMO were seen in the cerebrum as well as the optic nerves and spinal cord. This is the first autopsied case of NMO with a tumefactive cerebral lesion that later became cavitary.

Original languageEnglish
Pages (from-to)735-738
Number of pages4
JournalMultiple Sclerosis
Volume11
Issue number6
DOIs
Publication statusPublished - 2005 Dec
Externally publishedYes

Keywords

  • Autopsy
  • Bilateral optic neuritis
  • Cerebral lesion
  • Devic's syndrome
  • Neuromyelitis optica
  • Pathology
  • Transverse myelitis

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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