An Almost Quadratic Time Algorithm for Sparse Spliced Alignment

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    8 Citations (Scopus)

    Abstract

    The sparse spliced alignment problem consists of finding a chain of zero or more exons from O(n) prescribed candidate exons of a DNA sequence of length O(n) that is most similar to a known related gene sequence of length n. This study improves the running time of the fastest known algorithm for this problem to date, which executes in O(n2.25) time, or very recently, in O(n2log 2n) time, by proposing an O(n2log n)-time algorithm.

    Original languageEnglish
    Pages (from-to)189-210
    Number of pages22
    JournalTheory of Computing Systems
    Volume48
    Issue number1
    DOIs
    Publication statusPublished - 2011 Jan

    Keywords

    • Common substring alignment
    • Semi-local string comparison
    • String algorithm

    ASJC Scopus subject areas

    • Theoretical Computer Science
    • Computational Theory and Mathematics

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