Amino acid-induced responses in CNS neurones of normal mouse and wriggle mouse sagami

Katsutoshi Furukawa, Yumiko Abe, Nobutaka Osawa, Michio Ohmura, Norio Akaike

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Amino acid-induced responses and their regional heterogeneities in the motor cortical and hippocampal (CA1) neurones of normal mouse and Wriggle Mouse Sagami (WMS) were studied by conventional patch-clamp techniques. There were no differences in the current densities and EC50s of glutamate-, β-amino butyric acid (GABA)-, and glycine-induced responses between the two groups of mice. In both types of mice, the GABA-induced current density of cortical neurones was higher and EC50 was lower than in hippocampal neurones, whereas the responses induced by glycine and glutamate did not show any difference.

Original languageEnglish
Pages (from-to)1530-1532
Number of pages3
JournalNeuroReport
Volume5
Issue number12
DOIs
Publication statusPublished - 1994 Jul

ASJC Scopus subject areas

  • Neuroscience(all)

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