Pd/P(c-C6H11)3-catalyzed alkynyliminium ion cyclization in the presence of organoboronic acids affords stereodefined N-alkyl-3-alkylidenepyrrolidines. The distinctive cis-selective addition of the boronic acids and the iminium ions across the alkyne would result from favored 5-exo- or 6-exo-dig cyclization through oxidative addition of the formaldiminium ions to Pd(0).
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry