Alkylating probes for the G-quadruplex structure and evaluation of the properties of the alkylated G-quadruplex DNA

Norihiro Sato, Shuntaro Takahashi, Hisae Tateishi-Karimata, Madoka E. Hazemi, Tomoko Chikuni, Kazumitsu Onizuka, Naoki Sugimoto, Fumi Nagatsugi

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The G-quadruplex structure has been found in biologically significant regions of the genomic DNA, including the telomere and promoter regions, and is known to play an important role in a number of biological processes. In this paper, we report the development of alkylating probes for the G-quadruplex structure and evaluation of the properties of the modified G-quadruplex structure.

Original languageEnglish
Pages (from-to)1436-1441
Number of pages6
JournalOrganic and Biomolecular Chemistry
Volume16
Issue number9
DOIs
Publication statusPublished - 2018 Mar 7

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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