Aligning collagen fibers by cyclic mechanical stretch for efficiently muscle cell actuator

Keiji Seki, Masahiro Shimizu, Kota Miyasaka, Toshihiko Ogura, Koh Hosoda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Muscle cell actuators are composed of skeletal muscle cells and collagen intercellular matrix. Muscle cells adhere to collagen fibers and contraction along with the direction of collagen fiber. Collagen fibers in a muscle cell actuator transmit contraction force of each muscle cells along longitudinal direction. In order to improve contraction force of muscle cell actuators, it is very important to align collagen fibers. In this study, we aim to achieve alignment of collagen fibers in the actuator. We developed the automatic culture system which apply cyclic stretch to muscle cell actuators. We estimated the structure the actuator by using a scanning electron microscope and fluorescent observation. And we confirmed that cyclic stretch induced alignment of collagen fibers in the muscle cell actuators.

Original languageEnglish
Title of host publication2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1197-1202
Number of pages6
ISBN (Electronic)9781509043644
DOIs
Publication statusPublished - 2016 Jan 1
Event2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016 - Qingdao, China
Duration: 2016 Dec 32016 Dec 7

Publication series

Name2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016

Other

Other2016 IEEE International Conference on Robotics and Biomimetics, ROBIO 2016
CountryChina
CityQingdao
Period16/12/316/12/7

ASJC Scopus subject areas

  • Hardware and Architecture
  • Artificial Intelligence
  • Control and Systems Engineering

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