AgNTf2-mediated arylation of bromopyrroloindolines

Soichiro Sato, Azusa Hirayama, Tohma Adachi, Daichi Kawauchi, Hirofumi Ueda, Hidetoshi Tokuyama

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The silver(I)-mediated arylation of bromopyrroloindolines was developed. The selection of silver salts was crucial to obtain arylated compounds in high yields. Among the various tested silver(I) salts, AgNTf2 was the most effective agent for arylation. Reactions using various electron-rich aromatic compounds revealed that the developed conditions are suitable for the arylation of a broad range of aromatic compounds, including benzene derivatives, furan, thiophene, and pyrrole.

Original languageEnglish
Pages (from-to)1940-1957
Number of pages18
JournalHeterocycles
Volume94
Issue number10
DOIs
Publication statusPublished - 2017

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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