Age-specific trends in the incidence and in-hospital mortality of acute myocardial infarction over 30 years in Japan — Report from the miyagi ami registry study —

Yuanji Cui, Kiyotaka Hao, Jun Takahashi, Satoshi Miyata, Tomohiko Shindo, Kensuke Nishimiya, Yoku Kikuchi, Ryuji Tsuburaya, Yasuharu Matsumoto, Kenta Ito, Yasuhiko Sakata, Hiroaki Shimokawa

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Background: We are now facing rapid population aging in Japan, which will affect the actual situation of cardiovascular diseases. However, age-specific trends in the incidence and mortality of acute myocardial infarction (AMI) in Japan remain to be elucidated. Methods and Results: We enrolled a total of 27,220 AMI patients (male/female 19,818/7,402) in our Miyagi AMI Registry during the past 30 years. We divided them into 4 age groups (≤59, 60–69, 70–79 and ≥80 years) and examined the temporal trends in the incidence and in-hospital mortality of AMI during 3 decades (1985–1994, 1995–2004 and 2005–2014). Throughout the entire period, the incidence of AMI steadily increased in the younger group (≤59 years in both sexes), while in the elderly groups (≥70 years in both sexes), the incidence significantly decreased during the last decade (all P<0.01). In-hospital cardiac mortality significantly decreased during the first 2 decades in elderly groups of both sexes (all P<0.01), whereas no further improvement was noted in the last decade irrespective of age or sex, despite improved critical care of AMI. Conclusions: These results provide the novel findings that the incidence of AMI has been increasing in younger populations and decreasing in the elderly, and that improvement in the in-hospital mortality of AMI may have reached a plateau in all age groups in Japan.

Original languageEnglish
Pages (from-to)520-528
Number of pages9
JournalCirculation Journal
Volume81
Issue number4
DOIs
Publication statusPublished - 2017

Keywords

  • Acute myocardial infarction
  • Aging
  • Epidemiology
  • Sex

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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