AFM observation of extracellular matrix adsorbed on thermosensitive polymer-films in water

Hiroshi Sunami, Naoko Ido, Masaru Tanaka, Sadaaki Yamamoto, Masatsugu Shimomura

    Research output: Contribution to conferencePaperpeer-review

    Abstract

    Poly[2-(2-methoxyethoxy)ethyl methacrylate](PMEMA) with lower critical solution temperatures (LCST) of 22°C was prepared by free-radical polymerization of 2-(2-ethoxyethoxy)ethyl acrylate. The protein adsorption behavior was discussed by taking into account the changes in the surface properties of the polymer-films. There were much FBS proteins attached on the PMEMA films above the LCST compared to assays at lower temperature. Adsorption amounts of the proteins on the PMEMA films increased with increasing the temperature. These results showed that FBS protein adsorptions changed in surface properties governed by polymer transitions from hydrophilic to hydrophobic states.

    Original languageEnglish
    Number of pages1
    Publication statusPublished - 2005 Dec 1
    Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
    Duration: 2005 May 252005 May 27

    Other

    Other54th SPSJ Annual Meeting 2005
    CountryJapan
    CityYokohama
    Period05/5/2505/5/27

    Keywords

    • AFM
    • Cell adhesion
    • Scaffold
    • Thermosensitive polymer
    • Tissue engineering /

    ASJC Scopus subject areas

    • Engineering(all)

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